PDGF Skin Rejuvenation in Tucson, AZ

PDGF (platelet-derived growth factor) is a protein in your body that is involved in the healing process. At Facial Artistry & Aesthetics, we use Ariessence pure PDGF+, a topical form of this growth factor that is applied after select skin treatments, such as microneedling and laser resurfacing.

What it is: A topical growth factor
When it is used: After a skin treatment
Blood draw: None needed
Ingredients: Just four

What is PDGF?

Platelets, the tiny cell fragments in your blood that help it clot, release PDGF where tissue is damaged. After a skin procedure, your body releases PDGF where the skin was disrupted.

PDGF is built from two protein chains. The form in Ariessence, PDGF-BB, is made of two matching “B” chains.

What is Ariessence pure PDGF+?

Ariessence pure PDGF+ is a topical, post-procedure product from LRM Aesthetics, which launched it in 2024. It pairs PDGF with hyaluronic acid, which helps skin hold moisture.

The PDGF in Ariessence is made in a lab rather than taken from blood.

Who makes it

LRM Aesthetics, a company based in Franklin, Tennessee, and part of Lynch Regenerative Medicine.

How it is made

With recombinant technology: a gene for PDGF is placed into yeast, the yeast is grown in a sterile bioreactor, and the PDGF is then purified.

What is in it

Only four ingredients: water, sodium acetate, hyaluronic acid, and sh-polypeptide-59 dimer (the ingredient name for its PDGF-BB).

How does PDGF work?

PDGF works as a signal. It attaches to receptors on the surface of certain cells, especially connective tissue cells, and switches them on.

Once those receptors are active, the cells grow and divide, and they move toward the PDGF. Scientists call this directed movement chemotaxis.

In the body’s own healing process, LRM Aesthetics describes PDGF as gathering and activating healing cells such as fibroblasts, helping healthy cells multiply, encouraging new blood vessels to form, and stimulating the production of collagen and hyaluronic acid.

Ariessence is sold as a topical cosmetic, so its maker describes what it does in terms of how your skin looks, not as a treatment for any condition.

How is PDGF used with other treatments?

LRM Aesthetics designed Ariessence to be applied after treatments including microneedling, RF microneedling, laser skin resurfacing, and peels. The company says that, used this way, it can enhance your results and reduce downtime.

At Facial Artistry & Aesthetics, Ariessence PDGF can be added to select treatments, including SkinPen Microneedling, our Cool Peel laser, and ResurFX laser treatments. Our blog post on how Ariessence PDGF supports skin renewal shares more about how we use it.

Concerns its maker lists

LRM Aesthetics lists an improved appearance of skin texture, wrinkles, and pore size among the benefits of Ariessence.

How we use it at Facial Artistry

Your provider may also recommend Ariessence PDGF as part of a treatment plan for thinning hair, pigmentation, or under-eye hollows. Every plan is different, so your provider will talk with you at your consultation about whether it fits your goals.

What to expect

Your consultation

Your provider looks at your skin, your concerns, and your goals, and lets you know whether PDGF fits your treatment plan.
Your treatment

You have your planned treatment first, such as microneedling or a laser treatment.
Your PDGF

The PDGF and a hyaluronic acid serum are mixed, then rubbed onto the treated skin with a gloved finger. No blood draw is needed.

Is PDGF right for me?

Ariessence PDGF is added to another treatment, so whether it fits depends on that treatment, your skin, and your goals.

Your provider will confirm at your consultation whether Ariessence PDGF is a good fit for you.

PDGF FAQ

Is Ariessence PDGF FDA approved?

No. Ariessence is listed with the FDA as a cosmetic product, and cosmetics do not need FDA approval before they go on the market. Its maker markets it only as a topical cosmetic, not for injection.

Will I need a blood draw?

No. Ariessence is an off-the-shelf topical, and its PDGF is made in a lab, so it does not depend on your own blood or platelets.

Can PDGF be used on its own?

Ariessence is designed as a post-procedure topical. Its maker describes it for use after treatments such as microneedling, RF microneedling, laser skin resurfacing, and peels.

How long is recovery?

Recovery times vary from person to person and by procedure. Your provider will go over what to expect based on your treatment and your skin.

Does Ariessence contain human or donor material?

No. LRM Aesthetics makes its PDGF with recombinant technology, and the product has no human components. It is not derived from any human tissue or cells.